CHI Health Research

The CHI Health Research Center promotes innovative research efforts and is committed to providing quality healthcare for our patients and community


CHI Health Research Center is a keystone of our mission to nurture the healing ministry of the church, supported by education and research. The Center provides physicians and allied health care professionals with research support services necessary to conduct clinical research. As the primary teaching partner of Creighton University's health science schools, we are able to offer a full spectrum of research opportunities and lead efforts to discover, develop and optimize high quality care delivered to our patients.

What is a clinical trial?

A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people.

Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. 

Why participate in a clinical trial?

Participants in clinical trials can play a more active role in their own health care, gain access to new research treatments before they are widely available, and help others by contributing to medical research.

Who can participate in a clinical trial?

All clinical trials have guidelines for participation. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion criteria". These criteria are based on such factors as age, gender, the type and stage of a disease, previous treatment history, and other medical conditions. Before joining a clinical trial, a participant must qualify for the study. Some research studies seek participants with illnesses or conditions to be studied in the clinical trial, while others need healthy participants. It is important to note that inclusion and exclusion criteria are not used to reject people personally. Instead, the criteria are used to identify appropriate participants and keep them safe. The criteria help ensure that researchers will be able to answer the questions they plan to study.

What happens during a clinical trial?

The clinical trial process depends on the kind of trial being conducted. The clinical trial team includes doctors and nurses as well as other health care professionals like physical therapists, occupational therapists and pharmacists. They check the health of the participant at the beginning of the trial, give specific instructions for participating in the trial, monitor the participant carefully during the trial, and stay in touch after the trial is completed.

Some clinical trials involve more tests and doctor visits than the participant would normally have for an illness or condition. For all types of trials, the participant works with a research team. Clinical trial participation is most successful when the protocol is carefully followed and there is frequent contact with the research staff.  

How do I join a clinical trial?

  • Find a trial for which you would like to be considered.
  • Contact the Research Center.
  • We'll conduct a short phone interview to determine your eligibility for the trial.
  • Sign the informed consent form.
  • Report for your initial visit to participate in the trial