Alegent Creighton Health Research Center

CHI Health Research Center is a keystone of Alegent Creighton Health’s vision to be a leader among America's best health systems. The Center provides physicians with the tools necessary to conduct effective research.

CHI Health Research Center participates in clinical trials in a broad range of therapeutic areas, including: cardiovascular, orthopedics, oncology, womens' health, and infectious diseases. Through clinical research, physicians at CHI Health may offer their patients innovative, emerging treatments that are not currently available.

Participants in clinical trials play an active role in their own healthcare, gain access to new research treatments before they are widely available and help others by contributing to medical research.

What is a clinical trial?

A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people.

Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. 

Why participate in a clinical trial?

Participants in clinical trials can play a more active role in their own health care, gain access to new research treatments before they are widely available, and help others by contributing to medical research.

Who can participate in a clinical trial?

All clinical trials have guidelines about who can participate. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion criteria". These criteria are based on such factors as age, gender, the type and stage of a disease, previous treatment history, and other medical conditions. Before joining a clinical trial, a participant must qualify for the study. Some research studies seek participants with illnesses or conditions to be studied in the clinical trial, while others need healthy participants. It is important to note that inclusion and exclusion criteria are not used to reject people personally. Instead, the criteria are used to identify appropriate participants and keep them safe. The criteria help ensure that researchers will be able to answer the questions they plan to study.

What happens during a clinical trial?

The clinical trial process depends on the kind of trial being conducted. The clinical trial team includes doctors and nurses as well as other health care professionals. They check the health of the participant at the beginning of the trial, give specific instructions for participating in the trial, monitor the participant carefully during the trial, and stay in touch after the trial is completed.

Some clinical trials involve more tests and doctor visits than the participant would normally have for an illness or condition. For all types of trials, the participant works with a research team. Clinical trial participation is most successful when the protocol is carefully followed and there is frequent contact with the research staff.  

How do I join a clinical trial?

  1. Find a trial for which you would like to be considered.
  2. Contact the Research Center.
  3. We'll conduct a short phone interview to determine your eligibility for the trial.
  4. Sign the informed consent form.
  5. Report for your initial visit to participate in the trial.

Current clinical trials

CHI Health Research Center is currently enrolling participants in clinical trials.

  • Knee Injury - Call Terry Grindstaff at 402-280-5674 or complete the form.
  • Heart & Vascular
  • Cancer (Database maintained by The Missouri Valley Cancer Consortium. For more information, call 402-991-8070.)
  • Migraine/Premium Study
    CHI Health Research Center is conducting a trial for patients with disabling migraine headaches. The research study is designed to evaluate the safety and effectiveness of an investigational device as a treatment for migraine in subjects who are refractory to medical treatment.
    Call: 402-343-8511