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Aging changes in the male reproductive system
Aging changes in the male reproductive system may include changes in testicular tissue, sperm production, and erectile function. These changes usually occur gradually.
Andropause; Male reproductive changes
Unlike women, men do not experience a major, rapid (over several months) change in fertility as they age (like menopause). Instead, changes occur gradually during a process that some people call andropause.
Aging changes in the male reproductive system occur primarily in the testes. Testicular tissue mass decreases. The level of the male sex hormone, testosterone stays the same or decreases gradually. There may be problems getting an erection. This is a general slowing, instead of a complete lack of function.
The tubes that carry sperm may become less elastic (a process called sclerosis). The testes continue to produce sperm, but the rate of sperm cell production slows. The epididymis, seminal vesicles, and prostate gland lose some of their surface cells. But they continue to produce the fluid that helps carry sperm.
The prostate gland enlarges with age as some of the prostate tissue is replaced with a scarlike tissue. This condition, called benign prostatic hypertrophy (BPH), affects about 50% of men. BPH may cause problems with slowed urination and ejaculation.
In both men and women, reproductive system changes are closely related to changes in the urinary system.
EFFECT OF CHANGES
Fertility varies from man to man. Age does not predict male fertility. Prostate function does not affect fertility. A man can father children, even if his prostate gland has been removed. Some fairly old men can (and do) father children.
The volume of fluid ejaculated usually remains the same, but there are fewer living sperm in the fluid.
Some men may have a lower sex drive (libido). Sexual responses may become slower and less intense. This may be related to decreased testosterone level. It may also result from psychological or social changes due to aging (such as the lack of a willing partner), illness, chronic conditions, or medications.
Aging by itself does not prevent a man from being able to enjoy sexual relationships.
Erectile dysfunction (ED) may be a concern for aging men. It is normal for erections to occur less often than when a man was younger. Aging men are often less able to have repeated ejaculations.
ED is most often the result of a medical problem, rather than simple aging. 90% of ED is believed to be caused by a medical problem instead of a psychological problem.
Medicines (especially those used to treat hypertension and certain other conditions) can prevent a man from getting or keeping enough of an erection for intercourse. Disorders, such as diabetes, can also cause ED.
Erectile dysfunction that is caused by medicines or illness is often successfully treated. Talk to your primary health care provider or a urologist if you are concerned about this condition.
BPH may eventually interfere with urination. The enlarged prostate partially blocks the tube that drains the bladder (urethra). Changes in the prostate gland make elderly men more likely to have urinary tract infections.
Urine may back up into the kidneys (vesicoureteral reflux) if the bladder is not fully drained. If this is not treated, it can eventually lead to kidney failure.
Prostate gland infections or inflammation (prostatitis) may also occur.
Prostate cancer becomes more likely as men age. It is one of the most common causes of cancer death in men. Bladder cancer also becomes more common with age. Testicular cancers are possible, but these occur more often in younger men.
Many physical age-related changes, such as prostate enlargement or testicular atrophy, are not preventable. Getting treated for health disorders such as high blood pressure and diabetes may prevent problems with urinary and sexual function.
Changes in sexual response are most often related to factors other than simple aging. Older men are more likely to have good sex if they continue to be sexually active during middle age.
Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: An endocrine society clinical practice guideline. Journal Clin Endocrinol Metab. 2010;95:2536-2559.
Minaker KL. Common clinical sequelae of aging. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 24.
Reviewed By: Robert Hurd, MD, Professor of Endocrinology and Health Care Ethics, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.